Specialist centre for the treatment of heart and lung disease Royal Brompton and Harefield hospitals make up the largest specialist heart and lung centre in the UK and among the largest in Europe. Name:Dr Edward NicolEmail:E.Nicol@rbht.nhs.uk, Study Study Name: Dr Christoph NienaberEmail: c.nienaber@rbht.nhs.uk, Study A Phase 3b Open-label Study Evaluating the Long-term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor Combination Therapy in Cystic Fibrosis Subjects Ages 6 Years and Older Who Are Heterozygous for the F508del Mutation and a Minimal Function Mutation (F/MF)", Study contact information Dr Philip Molyneaux, Study Randomised controlled feasibility study of Maintaining the benefits of Pulmonary Rehabilitation with Harmonies and Melodies via Singing for Lung Health. Study Name:Mr AndreSimonEmail:A.Simon@rbht.nhs.uk, Study A Phase 3, Randomized, Double-Blind, PlaceboControlled Study to Evaluate Sotatercept When Added to Maximum Tolerated Background Therapy in Participants With Pulmonary Arterial Hypertension (PAH) World Health Organization (WHO) Functional Class (FC) III or FC IV at High Risk of Mortality. Name: Michelle RackhamEmail: M.Rackham@rbht.nhs.uk, Study Dr Rosemary Boyton, Study Inhalation challenge to assess Inducible Laryngeal Obstruction CHILO. A retrospective cohort study comparing the differences in baseline characteristics and outcomes in patients with influenza and COVID-19 treated with veno-venous extracorporeal membrane oxygenation (ECMO), Study contact information Name:Claire PrendergastEmail:c.prendergast2@rbht.nhs.uk. Real-world experience of dupilumab for the treatment of severe asthma in the United Kingdom: a retrospective study. A molecular toolkit for the microbial investigation of severe community acquired pneumonia (S-CAP Study), Study contact information Impact of premature birth on the gastrointestinal microbiota in early infancy and respiratory health at school age: a comparison of premature and term birth cohorts. A prospective, multicentre, randomised, blinded study of obstructive sleep apnoea detection using the Sunrise solution: The Sunrise OSA Trial (SOSAT), Study contact information Name:Richard MordiEmail:R.Mordi@rbht.nhs.uk, Study arlington cemetery gates; glass tumbler with bamboo lid bulk; 30Jun. Study We anaesthetise patients with severe pulmonary hypertension for various surgical and non-surgical procedures, both cardiac and non-cardiac. Name:Dr Louise FlemingEmail:l.fleming@rbht.nhs.uk, Study Dr. Benjamin Tam, MD, is an Orthopedic Surgery specialist practicing in Alhambra, CA with 31 years of experience. Dr Samantha Irving, Study Dr Julene Carvalho, Study Dietary nitrate supplementation to enhance daily physical activity in hypoxic COPD: a randomised controlled trial, Study contact information Study Phase III PoCC pivotal trial #1 BI 1015550 - PDE4 inhibitor in AF experienced PF-ILD. Study Name:Mindy GoreEmail:s.saglani@imperial.ac.uk, Principal investigator Name:Sally MeahEmail:S.Meah@rbht.nhs.uk, Study The effectiveness and risks of Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole (TIPAL): a randomised placebo-controlled multi-centre clinical trial, Study Name:Dr Ricardo JoseEmail:R.Jose@rbht.nhs.uk, Study Name:Cai SimEmail:c.sim@rbht.nhs.uk, Principal investigator An international patient-led registry in fibrotic interstitial lung diseases using eHealth technology. Managing abnormal glucose in cystic fibrosis (MAGIC)- the development of a self-management education programme for people with CFRD, Study contact information A Phase 2, Multi-Centre, Open-Label, Single-Arm Trial Investigating the Safety, Efficacy and Pharmacokinetics of C21 in Subjects with Idiopathic Pulmonary Fibrosis, Study contact informationName: Victor JardimEmail: V.Jardim@rbht.nhs.uk, Study Name: Professor Pallav ShahEmail: p.shah@rbht.nhs.uk, Study Study contact informationName: Professor Athol WellsEmail: RBHILD@rbht.nhs.uk, Principal investigator Royal Brompton Hospital is a regional centre for pulmonary hypertension in the UK. Narrow or blocked arteries. PAciFy Cough: A multicentre, double blind, placebo controlled, crossover trial of morphine sulfate for the treatment of PulmonAry Fibrosis Cough, Study contact informationName:Zhe WuEmail:Z.Wu@rbht.nhs.uk. A Phase 3 Open-label Study Evaluating the Longterm Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor Triple Combination Therapy in Cystic Fibrosis Subjects 2 Years and Older, Study contact information Name: Cristopher ShortEmail: C.Short@rbht.nhs.uk, Study Benjamin Garfield 1 , Charles McFadyen 2 , Charlotte Briar 2 , Caroline Bleakley 2 , Aikaterini Vlachou 2 , Melissa Baldwin 2 , Nick Lees 3 , Susanna . Improving outcome measures for physiotherapy trials of airway clearance in adults with CF, Study contact information Study Clinical Outcomes With Novel Modifier Therapy Combinations in CF, Study . Pulmonary hypertension in congenital heart disease, Study contact informationName: Dr Andrew ConstantineEmail: a.constantine@rbht.nhs.uk, Principal investigator Study contact information Name: Dr Ley Taing ChanEmail: l.chan3@rbht.nhs.uk, Study Efficacy of GLP-1 agonist Semaglutide in acute pulmonary embolisms: a biomarker-driven proof of concept open label phase II study, Study Deep learning for HRCT classification of fibrotic lung disease, Study The DEPICT study, Study contact information Name: Professor John PepperEmail: j.pepper@rbht.nhs.uk, Study A phase iii randomized, double-blind, placebo-controlled trial to evaluate the efficacy and safety of prm-151 in patients with Idiopathic Pulmonary Fibrosis. The Oxford Risk Factors And Non-invasive imaging Study. Name:Dr Christoph NienaberEmail:C.Nienaber@rbht.nhs.uk, Principal investigator Name:Paula RogersEmail:P.Rogers@rbht.nhs.uk, Study Study The UK Interstitial Lung Disease Long-COVID19 study (UKILD-Long COVID): understanding the burden of Interstitial Lung Disease in Long COVID, Study contact information Study contact information Professor Pallav Shah. Singing for Health: Improving Experience of Lung Disease, Study contact information Study HElping Alleviate the Longer-term consequences of COVID-19(HEAL-COVID): a national platform trial, Study contact information Name: Dr Anand DevarajEmail: A.Devaraj@rbht.nhs.uk, Study Professor Athol Wells, Study Name:Dr Johanna FearyEmail:J.Feary@rbht.nhs.uk, Study Clinical investigation of the VytronUS Ablation System for Treatment of Symptomatic Drug-refractory Paroxysmal Atrial Fibrillation (VITAL), Study contact informationName: Dr Tom WongEmail: T.Wong2@rbht.nhs.uk. Metatranscriptomics in Non-Tuberculous Mycobacterial Pulmonary Disease, Study contact information Myocarditis is a disease heart muscle caused by inflammation. AI & radiomics for Stratification Of lung Nodules After Radically treated cancer, Study contact information A double-blind, placebo controlled, multicentre, clinical trial to investigate the efficacy and safety of 12 months of therapy with inhaled Promixin (colistimethate sodium) in the treatment of subjects with non-cystic fibrosis bronchiectasis, Study Coagulation markers on discarded plasma samples from patients with severe COVID-19, Study contact information Summary Dr. Benjamin Tam, MD is a board certified orthopedic surgeon in Alhambra, California. Targets of bronchial thermoplasty in severe asthma, Study contact information Study contact information Study contact information Name:ChrisRemmingtonEmail:C.Remmington@rbht.nhs.uk, Study Perspectives On Screening and early Treatment for Pulmonary Fibrosis: a qualitative study, Study contact informationName: Dr Elizabeth RenzoniEmail: e.renzoni@rbht.nhs.uk. National cohort study of Idiopathic and Heritable Pulmonary Arterial Hypertension, Study contact information Name: Dr Mahmoud BarbirEmail: M.Barbir@rbht.nhs.uk. Digital tools in Heart failure patient and clinician perspectives, Study contact information Mechanisms of increased susceptibility to rhinovirus infection in frequent and infrequent exacerbators of Chronic Obstructive Pulmonary Disease, Study contact information Name: Dr Haseeb ValliEmail: h.valli@rbht.nhs.uk, Study Study contact informationName:Paula RogersEmail:p.rogers@rbht.nhs.uk, Study A placebo-controlled trial of percutaneous coronary intervention for the relief of stable angina, Study contact informationName: MerielWoodruffEmail:M.Woodruff@rbht.nhs.uk, Principal investigator Name: Dr Justin WangEmail: q.wang@rbht.nhs.uk. Fibrotic Interstitial Lung Disease and nocturnal oxygen - An observational study of the effects of nocturnal hypoxaemia on patients with fibrotic interstitial lung disease, Study contact information Name:Najwa SoussiEmail: n.soussi@rbht.nhs.uk, Principal investigator Study contact information Dr Stephen John Wort, Study A prospective safety and feasibility study of the RejuvenAir System metered cryospray therapy for Chronic Bronchitis patients, Study Patients Perception of Dry Powder Inhaler Airflow Resistance, Study contact information About | Expertise | Location | Research. Study A Multicenter, Randomised, Sham-controlled Study to Evaluate Safety and Efficacy After Treatment with the Nuvaira Lung Denervation System in Subjects with Chronic Obstructive Pulmonary Disease (COPD). Study contact information Asthma Exacerbation Profile in patients on open label treatment with Benralizumab for severe eosinophilic asthma - an exploratory cohort study, Study contact information Autoantibody Predictors of Long-Term Outcomes in Idiopathic Inflammatory Myopathy Associated Interstitial Lung Disease. Minimally invasive thoracoscopically-guided right minithoracotomy versus conventional sternotomy for mitral valve repair: a multicentre randomised controlled trial (UK Mini Mitral), Study contact information Prevention of post-operative complications by using HMG-CoA reductase inhibitor in patients undergoing oesophagectomy. Non-vitamin K antagonist Oral anticoagulants in patients with Atrial High rate episodes, Study contact information Name:Maria MartinsEmail:M.Martins@rbht.nhs.uk, Principal investigator Zephyrus II: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of Pamrevlumab in Subjects with Idiopathic Pulmonary Fibrosis (IPF). Study contact information Name:Ms Nicky MurrayEmail:N.Murray@rbht.nhs.uk. Dr SaeedMirsadraee, Study Clinical utility of non-invasive cardiac investigations following infection with COVID-19: a retrospective observational study, Study contact information Name:Dr Nicholas SimmondsEmail:N.Simmonds@rbht.nhs.uk. Study contact information Name: Dr Christopher OrtonEmail:c.orton@rbht.nhs.uk, Study Royal Brompton Hospital Contact: 020 7352 8121 ext 84133/ rbh-tr.thoraciccns-rbh@nhs.net Harefield Hospital Contact: 01895 828989/ rbh-tr.harefieldlungcns@nhs.net Administrative team Royal Brompton Hospital cancer team Maura Gallagher, cancer MDT co-ordinator Contact: 020 7352 8121 (ext 4303) Harefield Hospital cancer team Name:Angela AramburoEmail:a.aramburocaragol@rbht.nhs.uk, Principal investigator A double-blind, placebo-controlled study to assess the effects of inhaled PC945 in the treatment of culture-positive Aspergillus fumigatus infection in subjects with moderate to severe asthma, Study contact information National Validation and Sensitivity to Change of a scale to measure quality of life in patients with severe asthma. Dr. Benjamin C. Tam's office is located at 707 South Garfield Avenue, Alahambra, CA 91801. Professor Eric Lim, Study Study Name: Alkida BucajEmail: A.Bucaj@rbht.nhs.uk, Principal investigator Nasal Allergen Challenge: standardisation for house dust mite and silver birch allergen extracts, Study

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